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Anticoagulants: risk of major hemorrhage Contraindications Contraindications A condition or factor associated with a recipient that makes the use of a drug, procedure, or physical agent improper or inadvisable

For example, Hara et al reported that COL IV stimulates dendricity in human MCs on glass substrates (considered as ultra-hard stiffness) (Hara et al, 1994), while melanin production on stiff PDMS substrates (5.5 MPa) coated with laminin is higher compared to softer counterparts (from 50 kPa to 1.8 MPa) (Choi et al, 2014)

However, since the signalling pathway is complicated and bidirectional, application of BDNF in neuroprotection in humans remains to be elucidated

Each colour represents a different genus of bacteria, as indicated in the legend

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