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For weight management, medications like semaglutide 2.4mg (Wegovy) and liraglutide 3mg (Saxenda) are more restricted and typically initiated by specialist weight management services with specific BMI thresholds, not in general practice

doi: 10.1002/phar.2797 [PubMed] 37259844 Johannessen Landmark C, Eyal S, Burns ML, Franco V, Johannessen SI

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Blood-brain barrier considerations The blood-brain barrier (BBB) is both the brain greatest protector and the greatest obstacle to treating it