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In vitro hepatic models suggested that flavonoids and sulfur-containing compounds in garlic supplements might interfere with the activity of efflux drug transporters of the ATP-binding cassette (ABC) family, including P-glycoprotein, multidrug resistance protein (MRP), and breast cancer-resistance protein (BCRP), which function as ATP-dependent efflux pumps that actively regulate the excretion of a number of drugs limiting their systemic bioavailability

& Spaulding, H

Roy A, Chaudhuri J, Sarkar D, Ghosh P, Chakraborty S

Start 0.25 mg, increase 0.25 mg every 4 weeks to 2.4 mg maintenance (up to 4.5 mg)

(eds.) AkhtarMSwamyM.SinniahU

Refrigerate reconstituted vials at 28C