Exp Mol Med (2016) 48:e2244
For NAION, the risk appears higher with GLP-1 users who are obese and diabetic, though the available early data is incomplete. He believes the risk may be higher in patients with small optic nerve cups, sometimes described as a disc at risk. Regarding neovascular age-related macular degeneration, he said signals exist, though causality has not been established
May reduce severity of depressive symptoms in the elderly
[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Beddows C.A., Shi F., Horton A.L., Dalal S., Zhang P., Ling C.-C., Yong V.W., Loh K., Cho E., Karagiannis C., et al
Untreated Vitamin B12 deficiency can lead to neurological problems or pernicious anaemia, which occurs when our bodies don't have enough b12 to produce the amount of red blood cells it needs
When reviewing the database with NAD + precursors as interventions yet with the other term input using aging , it indicates that there are currently no ongoing or published clinical trials for NA, 2 trials exploring NAM, 4 trials examining NAD + , 5 trials investigating NMN, and 18 trials focused on NR in elderly cohorts