This triggers several beneficial effects: it stimulates insulin release when blood sugar levels rise, reduces the amount of glucose the liver produces, and slows down digestion so glucose enters the bloodstream more gradually
10.15252/emmm.202114753 EMBO Mol Med
Most guidelines recommend continuing titration unless medically contraindicated
A dose change under guidance may increase patient comfort and treatment adherence
(Migraines are considered chronic when someone has a headache on 15 or more days a month for at least three months.) The researchers divided the participants into two groups: Those who started taking a GLP-1 medication for another condition (such as type 2 diabetes or obesity) within a year of being diagnosed with chronic migraines, and those who started taking topiramate (a prescription medication used to prevent migraine headaches) during the same period
Antioxidant enzymes catalase, SOD, glutathione peroxidase, glutathione reductase, and thioredoxin act against the ROS