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[90] Endocrine effects may include suppression of the hypothalamic-pituitary-adrenal axis, which could lead to adrenal insufficiency if therapy is discontinued abruptly

Novo Nordisk's data exclusivity for semaglutide expired in Canada on January 4, 2026 [Source: glp1prices.ca/glp1-news/health-canada-reviewing-eight-more-generic-semaglutide-submissions-may-2026]

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Phase 1 involves enrolling 100 patients to a refined ePRO intervention, assessing initial outcomes, and gathering qualitative feedback from patients and providers through semi-structured interviews

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