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Broad interest is now focused on the biguanide metformin 37, 38 (see review in the same issue of this topical issue) as well as IR and IGF-1R inhibitors
It works by mimicking a hormone called GLP-1 (glucagon-like peptide-1), which helps to control blood sugar levels
But air travel hasnt decarbonised at all, yet it accounts for at least 2% of global carbon emissions
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Tirzepatide substantially reduces hunger but typically doesn't eliminate it entirely
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