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Common biomarkers used to identify senescent cells include the expression of p16 INK4a and p21 Cip1 , increased activity of SA--gal at pH 6.0, loss of the nuclear envelope protein Lamin B1, and the presence of persistent DNA damage foci [54]

FOR RESEARCH USE ONLY NOT FOR HUMAN OR ANIMAL CONSUMPTION NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE

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