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Safety endpoints across all PIONEER studies included the number of treatment-emergent adverse events, hypoglycemic episodes, laboratory tests, physical examinations, and predefined outcomes of special interest [38, 39, 61, 62, 76,77,78,79,80,81,82]

The outcome typically follows one of two paths: the victims money is stolen with no product delivered, or they receive unlabeled or mislabeled pills and liquids of unknown composition and safety

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