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Avoid use during pregnancy or active cancer

Hypothyroidism is one of the most commonly implicated conditions

Injectable GLP-1 has not been evaluated by the FDA, but side effects are expected to be similar to other GLP-1 based medications reviewed by the FDA, which have the following side effects: nausea, diarrhea, vomiting, constipation, abdominal (stomach) pain, headache, fatigue, dyspepsia (indigestion), dizziness, abdominal distension, eructation (belching), hypoglycemia (low blood sugar) in patients with type 2 diabetes, flatulence (gas buildup), gastroenteritis (an intestinal infection), and gastroesophageal reflux disease (a type of digestive disorder)

Because it is much less concentrated and diluted and wrapped with other botanical ingredients in this product, it will not react with GLP-1 in the gastrointestinal tract after entering the body

For longer-term storage, divide into sterile aliquots and store at -20C

A separate and equally important counterpoint: a detailed 2026 evidence review published by Barbell Medicine found that GLP-1 medications do not appear to cause muscle loss beyond what matched caloric restriction produces on its own