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Additionally, PCs alleviated DN pathology, such as glomerular basement membrane thickening and central dilatation, by modulating mimecan protein expression through the NF-B p65 pathway (Zhou et al., 2016) (Figure 8)

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Degradation accelerates above 4 degrees Celsius and with repeated freeze-thaw cycles

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In the balance beam test, Nrf2 KO mice showed a noteworthy increase in the time crossing the beam and a higher number of slips in the first week after post-MIA surgery (Fig