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Common side effects can include nausea, constipation, diarrhea, vomiting, stomach discomfort, or fatigue

If you notice a consistent downward trend in your weight, it may indicate that semaglutide GLP-1 is effectively supporting your weight loss goals

Clinical trials show tirzepatide producing slightly greater average weight loss, with participants losing 15 to 21 percent of body weight compared to 15 to 17 percent with semaglutide

For weight management, some patients may attempt discontinuation after achieving goals, though most will require ongoing treatment to maintain weight loss

Read here for more information on the class of drugs known as GLP-1 agonists

We speculate that a fraction of the purified receptor complex may bind Gs in the absence of the agonist