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Investigators repeated the analysis with cohorts of patients without psoriasis

Glucagon-like peptide-1 receptor analogs (GLP-1RAs) intake associates with lower serum TMAO concentration in MetaCardis T2D participants Given the strong bidirectional connection we uncovered between serum TMAO and eGFR, we hypothesized that use of reno-protective medication could be linked with lower circulating TMAO

These pathways drive oxidative stress and inflammation, accelerating pericyte loss and blood-retinal barrier (BRB) breakdown

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10.1038/s41392-020-00373-7 6

Safety Profile for Metabolic Health The preservation of normal glucose metabolism makes AOD-9604 particularly valuable for individuals with metabolic syndrome, insulin resistance, pre-diabetes, or type 2 diabetes who seek fat loss support