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12 Conclusion CUL5, as the core scaffold protein of the Cullin-RING ligase 5 (CRL5) complex, plays a crucial role in the initiation and progression of malignant tumors by regulating the stability of diverse substrate proteins through the ubiquitin-proteasome system

Photosynthetic tumor oxygenation by photosensitizer-containing cyanobacteria for enhanced photodynamic therapy

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The TRANSCEND-T2D-1 trial demonstrated A1C reductions of up to 2.0% and weight loss of up to 16.8% at 40 weeks, with no plateau observed through the end of the treatment period

doi: 10.1016/j.molcel.2018.03.018 36 PuckettDLAlquraishiMChowanadisaiWBettaiebA