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Activation of the SIRT6-AMPK signaling pathway by GLP-1RAs may therefore represent an attractive therapeutic strategy to prevent the development and progression of NAFLD and related cardiovascular diseases by modulating cholesterol metabolism
Primary source: EXSCEL Trial New England Journal of Medicine Is exenatide still used
37, 225e8
Effects of GLP-1 receptor agonists on fracture risk in humans The STEP program, consisting of phase 3 randomized controlled trials, has examined the effectiveness of semaglutide (Wegovy) in treating obesity [18, 19]
Although several investigations have revealed that D-allulose has antidiabetes activity, the mechanism has yet to be fully elucidated
10.1111/j.1365-2133.2009.09594.x
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