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The SURMOUNT-1 trial demonstrated substantial weight loss benefits in patients with obesity

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Any disruption of the normal function of the ER, especially oxidative stress, can lead to ER stress, which is characterised by an accumulation of misfolded or unfolded proteins in the ER lumen

Both dimethyl fumarate and its active metabolite, monomethyl fumarate, promote NRF2 nuclear translocation and the subsequent transcription of antioxidant response element (ARE)-driven genes

However, beyond its recreational appeal, THC boasts several medical benefits