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Joint discomfort and mild edema (water retention) are documented side effects of sustained IGF-1 elevation, occurring in approximately 1525% of users

Rueda-Clausen C.F., Silva F.A., Lpez-Jaramillo P

This does not mean every patient has to give up alcohol

The apoptosome: signalling platform of cell death

Similarly, signs of severe dehydrationincluding decreased urine output, dark urine, extreme thirst, dry mouth, or dizziness that improves minimally with fluid intakerequire medical assessment

Because of genetics, some people with certain genetic snips may have sensitivities to it and may need to begin with very small doses