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Szatrowski TP, Nathan CF

A review in PMC reported that higher GGT was linked with a 100% increased risk of all-cause mortality in high-risk groups, a 130% higher risk for cancer mortality, and a 60% higher risk for vascular and ischaemic heart disease over 19 years of follow-up (PMC review on GGT and cardiometabolic risk)

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1, which provides a conceptual framework that bridges the design considerations discussed in Sect

This suggests that MORs on PVN Glu neurons may influence colonic water absorption, but not appear to directly regulate colonic motility