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Not because they lack the will

Randing on a scale of 0 to 1with values closer to 1 showing a greater treatment effect the CEI factors in seven different data points: Body weight, waist circumference, HbA1c (blood sugar levels), systolic blood pressure, triglycerides, HDL cholesterol, and LDL cholesterol

When you have been fat for a decade and you finally decide to do something about it, every day of delay feels like a personal insult

Self-reported weight loss looked materially larger than EHR-recorded weight loss, with a median BMI change of -11.8% in surveys versus -5.79% in EHR data

and SURMOUNT-OSA looked at tirzepatide in obstructive sleep apnea (NEJM, 2024)

AASLD practice guidance: palliative care and symptom-based management in decompensated cirrhosis