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It belongs to a class of medications called thyroid hormone receptor (THR)-beta agonists Its important to get regular checkups, especially if you have risk factors for MASH, such as Type 2 diabetes, high cholesterol, high triglycerides, high blood pressure, insulin resistance, obesity, or being overweight

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It is known that the polar residues that reside within the TMD regulate biased signaling of the receptor (3), while the transmembrane helical boundaries and extracellular surface are a trigger for biased agonism (4)

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