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A comparative study of obese and lean rats found that lean rats showed greater drops in estrogen and vitamin D and higher urinary calcium excretion after weight loss, suggesting increased sensitivity to calcium disturbances

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doi: 10.1186/s12902-017-0155-9 159 PapaetisGSFilippouPKConstantinidouKGStylianouCS

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Neuronal effects of GLP-1MK-801 To understand the biological underpinnings of the metabolic benefits of GLP-1MK-801, we performed RNA sequencing (RNA-seq) and MS-based proteomics analyses on hypothalami from DIO mice treated with vehicle, GLP-1, MK-801 or the GLP-1MK-801 conjugate for 5 days (Fig