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Discontinue Use: If irritation, redness, or an allergic reaction occurs, discontinue use and consult a healthcare provider.

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In this case, the -hairpin (22) is absent but a long C-terminal extension, which extends the -sheet structure, prevents the formation of the classical dimer (Figure S1B)

The activity of these enzymes is enhanced by a variety of chemicals, including caffeine[40, 41] and anticonvulsant drugs[42], and it is well known that co-ingestion of these drugs with APAP can greatly enhance the toxicity of APAP

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