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Reduced IGF-binding protein affinity leaves more free peptide for IGF-1 receptor activation, yielding roughly 210 potency vs native IGF-1 in preclinical assays but a very short ~2030 minute half-life

At the cellular level, chronic hyperglycemia initiates several pathogenic mechanisms

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Still, oral options will likely impact the market positively in terms of accessibility (an option for needle-phobic patients) and affordability

Growth hormone plays an essential role in repairing tissue and helps the body recover from injury

This is, I think, a peptide that we're gonna see utilized to stabilize connective tissue in these individuals