Reduced appetite often leads to: Reduced total protein intake Smaller portion sizes Reduced resistance training capacity Clinical trials suggest a proportion of weight loss may include lean mass when protein intake is inadequate. Loss of lean mass may indirectly influence: Iron status Functional strength Resting metabolic rate Protein adequacy is therefore one of the most important nutritional variables during GLP-1 therapy
Direct immunomodulation is achieved through bioactive components such as TGF- (Transforming Growth Factor-beta), which enhance the differentiation and function of regulatory T cells (Tregs), thereby enhancing peripheral immune tolerance [14, 15]
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But the study is not peer-reviewed, and three doctors who spoke with Fortune raised concerns about it being unclear on its methods, inclusion and exclusion criteria, other medications or surgeries that may not be accounted for, and whether participants continued a planned diet and exercise regimen post-medication
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Can I get enough protein from food alone while on GLP-1