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Description

These reports are anecdotal and do not constitute clinical evidence

Published human data are limited and consist mainly of pilot studies and retrospective observations

Nec-1 functions through the specifically targeting of Receptor-Interacting Protein Kinase 1 (RIPK1), inducing disruption in the assembly of the necrosome, consequently impeding the execution of necroptotic cell death

dose and schedule depend on the protocol and clinicians plan