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Cell culture and characterization The human BBB co-culture model based on stem cell-derived endothelial cells (hEC) and brain pericytes (PC) were established and characterized by the group of Ceccelli et al

doi: 10.3390/diseases12090224

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Cardiac targeting peptide: from identification to validation to mechanism of transduction

These events collectively result in mitochondrial dysfunction, elevated ROS, and impaired protein clearance, the triad that drives S misfolding and aggregation