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For the biochemical assays, both hippocampi were extracted on a cold petri dish and snap-frozen immediately on dry ice to be stored at 80 C until analysis

SAM, a key methyl donor, is derived from folate/one-carbon metabolism and the methionine cycle, with its levels regulated by mitochondrial metabolism, thereby controlling the supply of methylated substrates [250]

It should not be crushed, cut, chewed, dissolved, shared with others, or taken more than once daily

Output: Volume to draw up (ml and IU)

This effect is not replicated by GLP-1R or GIPR agonism alone