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The use of Contrave has been approved for adults who have a BMI (body mass index) of thirty or greater which indicates obesity, or a BMI of twenty seven or greater which means they are overweight and have at least one condition that is related to weight, for example type 2 diabetes, high blood pressure or high cholesterol

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2018;13(4):e0196314

Treatment through NHS specialist services typically continues for up to 2 years, and discontinuation often results in weight regain

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