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2 Weight and mood: a connected relationship Theres a well-established link between obesity and mental health conditions like depression

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The incidence of hypoglycemia was reported as low across treatment groups, consistent with the glucose-dependent insulin secretory mechanism attributed to incretin receptor agonism

Also, it would be preferable to have an MC4R-KO mouse group with a chow diet to observe the difference in disease progression compared to the WD-fed mice

The main chain CO group of Ser 2P forms an H-bond with the side-chain of R102 2.63 , which is critical for ghrelin binding (Fig