This action helps reduce overall calorie intake and prevent overeating, making it a crucial tool for chronic weight management
Results published in 2025 reported meaningful weight loss with oral semaglutide 25 mg compared with placebo, alongside lifestyle changes
4,5 Dietary insufficiency, pernicious anemia (i.e., an autoimmune process that reduces available intrinsic factor and subsequent absorption of vitamin B 12 1,2,6,7 ), and long-term use of metformin or acid-suppressing medications have been implicated in B 12 deficiency
The drug creates a positive feedback loop where weight loss improves the metabolic environment, which makes further metabolic normalization easier
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[DOI] [PubMed] [Google Scholar] 75.Batista A.F., Bodart-Santos V., De Felice F.G., Ferreira S.T