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Patients typically choose the most convenient route when efficacy and safety are comparable

semaglutide has more extensive cardiovascular outcome data Cardiovascular Disease: Semaglutide has proven heart benefits in SELECT trial Kidney Disease: Dosing adjustments may be needed for both Gastrointestinal Issues: Pre-existing GI problems may influence tolerance Lifestyle Factors: Neither medication works without lifestyle changes

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This is because the risk of toxicity and serious adverse effects from an overdose is rare

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