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The largest psychiatric meta-analysis to date 80 randomized controlled trials, over 107,000 patients also found significant improvements in restrained eating and emotional eating with GLP-1 medications compared to placebo ( Pierret et al., JAMA Psychiatry, 2025 )

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, which have surged in popularity due to their effectiveness in Previous studies have produced mixed results on whether these drugs are associated with eye complications, with some analyses finding a modest increase in NAION risk and others finding no elevated risk

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