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The 48 week BELIEVE Phase 2 compared a multiple placebo arm to semaglutide4 (1.0mg or 2.4mg), bimagrumab (10 mg/kg, 30 mg/kg), and sema-bima (1.0mg, 2.4mg semaglutide X 10 mg/kg, 30 mg/kg bimagrumab)

Off-label use in younger patients occurs in clinical practice, but such decisions require careful provider assessment of risk-benefit, family history, and metabolic status

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According to the pivotal TRIUMPH-1 trial results, participants experienced up to 28.3% average weight loss over 80 weeks