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If your deficiency stems from a condition like pernicious anemia that permanently affects absorption, you'll likely need injections every 1-3 months for life

In 2023, the FDA classified it as a Category 2 bulk drug substance , meaning it cannot be legally compounded by commercial pharmaceutical compounding pharmacies in the United States

Vitamin B12 (cobalamin) injections are a form of intramuscular treatment used to rapidly restore and maintain adequate B12 levels in the body

These individuals may benefit from this enhanced oral option

Those who have had bariatric surgery or other gastrointestinal procedures often have less stomach surface area available for vitamin absorption

In StatPearls