prediabetes and glp 1 GLP-1 Medications – Community Education GLP-1R signalling promotes β-cell glucose

According to FDA prescribing information, these include: Nausea (occurring in 1544% of patients depending on formulation and dose) Vomiting (524% of patients) Diarrhea (830% of patients) Abdominal pain (511% of patients) Constipation (324% of patients) These gastrointestinal symptoms typically emerge during dose escalation and often diminish over time as physiological tolerance develops

Bishehsari F, Magno E, Swanson G, Desai V, Voigt RM, Forsyth CB, Keshavarzian A

Pharmacol Rev (2008) 60:470512

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Though some influencers promote weight-loss drugs, the results can vary widely

In short, they found that while consumers, employers and physicians are optimistic about the effectiveness of GLP-1s to treat obesity, cost and coverage are significant hurdles for consumer access