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Even the most efficient transport from clinic or GP practice to laboratory centrifuge rarely renders this feasible

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Getting a drug through FDA approval costs $1-2 billion on average and takes 10-15 years

You spent the dose and got a fraction of the response

Supraphysiological testosterone concentrations have been shown to reduce endothelial nitric oxide synthase expression and nitric oxide bioavailability, thereby favouring vasoconstriction and increased arterial stiffness (73)