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A.StevensC.van DyckK.BergmanA.YiB.de SmetM.et al (2005)

European j Mol Biol Biochem 198(2):317326

This reduced response is driven by insulin resistance, diabetic medications (some of which promote weight gain), and metabolic dysfunction that blunts the full effect of GLP-1 therapy

For the future of metabolic therapeutics, survodutide's Phase 2 data are encouraging, particularly for MASH where the glucagon mechanism provides a uniquely differentiated approach

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