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It co-localizes with multiple hormones and neurotransmitters, suggesting broad regulatory functions

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26 The weight-loss effects of GLP-1 RAs have been attributed not only to appetite-suppressing mechanisms but also to increased energy expenditure through activation of hindbrain pathways and stimulation of thermogenesis in brown adipose tissue

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All CMR values were compared to published published 95% confidence interval 12

Interestingly, a retrospective analysis of 202 UC patients showed that higher BMI was inversely related to disease severity and IBD extent (88)