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Each freeze-thaw cycle multiplies this damage

Carnitine, with its antioxidant properties, helps mitigate oxidative damage by scavenging free radicals, protecting sperm mitochondria from oxidative stress, which is particularly important in the preservation of sperm motility and overall fertility

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26 Nonetheless, these ferroptosis inhibitors have been demonstrated to prevent cellular damage and death in a wide range of ex vivo and in vivo models of acute and chronic pathological cell death, 2,13,26,32 and testing in more complex diseases models or human clinical trials should be anticipated in the future