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Review on the artificial intelligence-based nanorobotics targeted drug delivery system for brain-specific targeting

PLoS ONE 10 , e0137750 (2015)

From this perspective, we see a few major concerns with GLP-1s: They do not address root causes

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Existing and Emerging Molecular Targets for the Pharmacotherapy of Obesity

Heres a look at common biologic classes and their half-lives: o Humira (adalimumab): 68 weeks o Enbrel (etanercept): 2 weeks o Remicade (infliximab): 46 weeks o Cosentyx (secukinumab): 4 weeks o Stelara (ustekinumab): 12 weeks o Tremfya (guselkumab): 8 weeks o Xeljanz (tofacitinib): 12 weeks o Rinvoq (upadacitinib): 12 weeks A common approach physicians might take to accommodate for the variation in drug half-lives is to stop one full dosing interval before major implant surgery for each biologic, with consideration for a longer hold where theres a high risk for infection or poor wound healing