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Key Efficacy Comparison Year 1 Outcomes: For chronic weight management in adults without diabetes, tirzepatide 15 mg achieved a mean 22.5% total body weight reduction in SURMOUNT-1 (N Engl J Med, 2022), while semaglutide 2.4 mg delivered approximately 15% in the STEP program

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How to Safely Combine Intermittent Fasting and GLP-1 Weight Loss Drugs Combining intermittent fasting with GLP-1 medications like semaglutide or tirzepatide can be an effective way to support weight loss, improve blood sugar regulation, and simplify your approach to eatingbut only if done correctly

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