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In vitro DDI studies detailed in clinical pharmacology and biopharmaceutics reviews were not included for exenatide and dulaglutide, but were included for liraglutide, semaglutide, and tirzepatide (Table 3).39,5658,139 All the investigated GLP-1 RAs and a dual GLP-1/GIP RA exhibited minimal inhibition or induction of CYP enzymes

BohulaEASciricaBMInzucchiSEMcGuireDKKeechACSmithSRet al

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The claim of a favourable benefit-risk profile seems to be a bit of a judgment call, theres not much more weight loss and not many more other health benefits than with semaglutide 2.4mg and the adverse events, particularly the Dysaesthesia cluster experienced by more than 22% of the 7.2mg group, seem concerning to me

The trial results add to the growing list of conditions that GLP-1s the class of drugs that includes Novo Nordisks Ozempic and Wegovy and Eli Lillys Mounjaro and Zepbound can treat beyond diabetes and weight loss

Our ability to produce and maintain a high glutathione level in our bodies is critical to recovering from chronic illnesses