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These processes do not only depend on intracellular dynamics of hepatocytes, but are in part regulated by intercellular signaling between hepatocytes and immune cells such as the livers resident Kupffer cells (KCs) and recruited monocyte-derived macrophages (ms) 14

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Because crystalline CoQ10 has low water solubility and poor powder dispersibility, its commercial performance depends strongly on carrier oil selection, particle-size control, and dosage-form engineering

The carnitine transport mediated by OCTN2 is Na + -dependent

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