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Reports indicate that a significant proportion of cases show no detectable spinal cord lesions, and excessive reliance on imaging may delay treatment [9,10]

Preclinical studies using T4 (including the RGN-259 ophthalmic clinical trials) have not identified significant adverse events at therapeutic doses

The outer thigh has fewer nerves and blood vessels, which helps reduce the discomfort associated with the injection

This is consistent with previous studies of the amylin analogue, pramlintide