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Optimization of Targeted Strategies Surface modification: By adjusting the surface properties of the drug carrier, such as increasing the surface density of the targeting ligand or changing the charge properties on the carrier surface, the targeting ability of BPC 157 can be improved

Drach J, Pereira-Leahy M, Sanchez-Williams G, Dunne C, Zhao S, Liu Y, Estey E, Andreeff M

PMID 12011145

For some other types of affinity purifications, like Nickel Beads and His-tags, regeneration means that we actually strip the nickel ion off of the beads and regenerate them by adding new nickel onto the beads

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