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In MCAS, mast cells become overly sensitive , releasing mediators inappropriately or excessively, even without a clear external trigger

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Recent nutritional approaches to the prevention and therapy of cardiovascular disease, Prog Cardiovasc Nurs 1997Summer;12(3):3-23

Effect of menopausal status on carotid intima-media thickness and the presence of carotid plaque in Chinese women generation population