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This previously unrecognized mechanism highlights cuproptosis as a novel therapeutic vulnerability in anti-androgen-treated PCa and offers new insight into resistance modulation and treatment optimization

A healthy volunteer pharmacokinetic study showed persisting levodopa plasma levels over 8 h [25] but no further development data have been reported

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In bladder cancer cells, the poor permeability of Asp cells prevents the uptake of Asp by tumor cells from the environment

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