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38, 39, 40, 41, 42 An increased expression of these cytokines may result in enhanced production of tissue repair molecules

Add 80 l 10 mM HCl, and lyse the cells by freezing and thawing twice

doi: 10.1177/02601060211073236 102

At higher concentrations, it decreases MMP2 and MMP9, protecting newly formed structural proteins from degradation

In the cerebellum, which is increasingly recognized for its contributions to ASD core symptoms (DMello and Stoodley, 2015), BTBR mice show increased NFB and iNOS expression as well as lipid peroxides, indicative of increased oxidative stress (Nadeem et al., 2019)

This lack of treatment options may in part be due to the nature of ASD as a highly heterogeneous neurodevelopmental disorder encompassing a wide range of presentations and severities