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We therefore generated new cohorts of mice lacking Gipr in the hypothalamus (Gipr hypo-KO ), by targeted injection of AAV-Cre or control AAVGFP (Gipr hypo-GFP ) into the paraventricular nucleus (PVN) (Fig

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Complete week-by-week combined protocol The following protocol represents a conservative approach to introducing both compounds, designed to minimize GI side effects while building toward full therapeutic doses

[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Sindhwani R., Bora K.S., Hazra S