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The review described direct effects on NK cell cytotoxicity, T-cell proliferation, and macrophage function, along with antimicrobial effects against intracellular pathogens including Mycobacterium tuberculosis (Ghezzi, 2011)

they are summarised here for the benefit of researchers designing in-vitro or animal studies

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Clinical guidelines and physiological evidence have supported the management of overweight and obesity as an important strategy to reduce blood pressure and cardiovascular risk

The FLOW trial was stopped early because the kidney benefit was already clear, a rare and meaningful signal